5-Methoxyindole

Product 2-ethyl-4-methoxy aniline is considered as a promising raw material with big potential for producing 5-methoxy indole,an important fine chemical used in synthesis of indole derivatives.

以氯霉素的副产物邻硝基乙苯为原料,经Bamberger反应、乙酰化反应、o-甲基化反应和水解反应4步合成了可作为5-甲氧基吲哚合成原料的2-乙基-4-甲氧基苯胺;对该工艺路线的关键步骤Bamberger反应进行了工艺条件优化。