simian virus 40

SV40T antigen acts as a potent growth stimul.

猿猴病毒40T(SV 40T)是一种病毒癌蛋白,其与肿瘤抑制蛋白p53和R b结合,并使之失活,从而消除它们抑制细胞生长的功能,使细胞分裂加速,形成肿瘤。

SV40Tag was subcloned into pMM279 and the recombinant vector was used to generate transgenic mice by microinjection.

将猿猴病毒抗原蛋白(SV40Tag)片段克隆进脑部特异表达载体pMM279中,通过显微注射法制作转基因小鼠。