MPF(mitosis - promoting factor)

PrefaceOur lab group previous work has demonstrated that both protein kinase A (PKA) and prtein kinase C (PKC) are important elements to regulate the activity of M - phase promoting factor (MPF) in signal transduction pathway of mouse zygote early development.

前言 我们的前期工作已经证明了在小鼠受精卵早期发育信号传导过程中,蛋白激酶A(PKA)和蛋白激酶C(PKC)是调节有丝分裂促进因子(MPF)活性的重要物质。

MII eggs are characterized by high activity of mitogen - activated protein kinase ( MAPK ) and maturation promoting factor( MPF).

前言 包括哺乳动物细胞在内的很多物种卵母细胞减数分裂停滞于MⅡ期直到受精,此期丝裂原活化的蛋白激酶(MAPK)和有丝分裂促进因子(MPF)维持高活性状态。

OBJECTIVE:To explore the relationship between expressions of endoglin(CD 105),vascular endothelial growth factor(VEGF),mitotic inhibitor/suppressor protein (p57 kip2) and histopathological profiles, natural history in human hepatocellular carcinoma (HCC).

目的:探讨肝细胞癌(hepatocellular carcinoma, HCC) endoglin ( CD105 )、血管内皮生长因子( vascular endothelialgrowth factor, VEGF)和有丝分裂抑制因子(p57kip2)的表达与组织形态学和自然病程的关系。