folyl monoglutamate

As one of the key-enzymes in folic acid metabolic pathway, Folylpolyglutamate synthetase (FPGS) content and activity directly associated with the effects of MTX.

背景:氨甲蝶呤(Methotrexate,MTX)是许多叶酸途径抗肿瘤药物的前体,存在L-(+)-MTX和D-(-)-MTX 2种形式的对映体,广泛应用于淋巴瘤、急性白血病和肺癌等多种肿瘤的治疗,作为MTX代谢途径中的关键酶之一的细胞内叶酰聚谷氨酸合成酶(folylpolyglutamate synthetase,FPGS),其含量和活性直接与MTX作用效果相关,已成为当今研究的热点,但有关FPGS定量检测的报道甚少。

Cloning and Expression of N-acetylglutamate Kinase Gene from Corynebacterium Crenatum;

钝齿棒杆菌N-乙酰谷氨酸激酶编码基因argB的克隆表达研究

Expression Profiling of Intestinal N-Acetylglutamate Synthase in Pre-Weaned Tibetan Suckling Piglets

哺乳期藏猪肠道N-乙酰谷氨酸合成酶在哺乳期的表达特性

Expression,Purification and Biochemical Characterization of N-Acetylglutamate Kinase from Streptococcus mutans,the Leading Pathogen of Human Dental Caries

致龋变异链球菌N-乙酰谷氨酸激酶的表达、纯化和生化特性研究

Synthesis of N-acetyl-aspartyl-glutamate-a kind of nerve dipeptide

神经二肽N-乙酰天门冬氨酰谷氨酸的合成

Effect of Glutathione and N-acetylcysteine Against Glutamate Cytotoxicity;

谷胱甘肽及N-乙酰半胱氨酸抗谷氨酸细胞毒性研究

Aspartic acid An AMINO ACID formed by transamination, in which the amino group of dlutamic acid is transferred to oxaloacetic acid.

天冬氨酸：由转氨基作用形成的一种氨基酸，谷氨酸的氨基基团被转移到草酰乙酸中。

The Enzymatic Synthesis of γ-L-glutamyl-L-tyrosine with γ-glutamyltranspeptidase

γ-谷氨酰转肽酶法合成γ-L-谷氨酰-L-酪氨酸

Study on Synthesis of 5-Aminolevulinic Acid Based on the Levulinic Acid

乙酰丙酸合成5-氨基乙酰丙酸的研究

glutamate oxaloacetate transaminase

谷氨酸 草酰醋酸氨基移转酶

acetylaminohydroxy-phenylarsonic acid

乙酰氨基羟－苯胂酸

uramildiacetic acid 2-

氨基丙二酰脲二乙酸

3-acetamido-4-hydroxy-benzenearsonic acid

３－乙酰氨－４－羟苯砷酸

aminolevullnate dehydratase

σ-氨基乙酰丙酸脱水酶

N-hydroxyacetylneuraminic acid

Ｎ－羟乙酰神经氨酸

Study on Acetylcholine Potentiating Glutamate Neuronal Excitotoxicity and Its Mechanism of Receptors during Cerebral Ischemia

脑缺血时乙酰胆碱加强谷氨酸的神经兴奋毒性及受体机制研究

Effect of the Glyoxylate Cycle on L-Glutamate Synthesis by Corynebacterium Glutamicum;

谷氨酸棒杆菌的乙醛酸循环与L-谷氨酸合成

Enzymatic Synthesis of γ-L-Glutamyl-L-Cysteine with Immobilized γ-Glutamyltranspeptidase

固定化γ-谷氨酰转肽酶催化合成γ-L-谷氨酰-L-半胱氨酸

diminazene aceturate

重氮氨苯脒乙酰甘氨酸盐