scrapie-associated fibril

To understand the characteristics of PrP Sc molecules and deposits in spinal cords and other peripheral tissues in hamster infected with scrapie strain 263K in five challenge pathways.

目的　比较研究实验仓鼠经不同途径感染羊瘙痒病 (Scrapie)毒株 2 6 3K的终末期病鼠脑外组织内PrPSc分子和沉积特点。

The results showed that protease\|resistant pathological PrP SC was existed in golden hamster brain tissue which was inoculated with scrapie strain 263 K, but no protein e.

根据致病型朊病毒 (PrPSC)能抵抗蛋白酶消化的特性 ,用蛋白酶K消化脑组织提取物 ,以抗体T1进行免疫印迹反应 ,结果表明从接种羊瘙痒病朊病毒 2 6 3K的金黄地鼠脑组织提取物内检测到抗蛋白酶K消化的致病型PrPSC ,而正常金黄地鼠脑组织中没有抗蛋白酶消化的蛋白。

Mouse-adapted scrapie strain 139A can overcome species barrier to induce spongiform encephalopathy in golden hamster;

羊瘙痒病小鼠适应株ME7可突破种属屏障颅内感染金黄地鼠

The contents of total tau increased, but phosphorylated tau at Ser396 and Ser404 decreased, regardless of the types of scrapie agents and clinical incubations.

为探讨朊病毒病的神经病理特征,应用Western blot方法检测了感染羊瘙痒因子263K株或139A株的仓鼠脑组织中总tau蛋白和Ser396和Ser404位点发生磷酸化tau蛋白表达水平的变化;并应用Real Time PCR方法检测了tau mRNAs转录活性的改变。

Analysis of the Changes of tau in Scrapie-infected Hamsters and in CSF of Creutzfeldt-Jakob Disease

本文分为两部分,第一部分我们分别采用Western blot和real-time PCR方法检测了感染羊瘙痒因子的仓鼠脑组织中tau蛋白、磷酸化tau蛋白和蛋白激酶在表达和转录水平上的变化,以揭示这些生物活性蛋白与TSE发病机制之间的潜在联系。

Any one of those would destroy a bacterium or a virus. But not BSE, CJD or scrapie.

这些方法中的任何一种都可以破坏细菌或是病毒，然而对于BSE、CJD或羊瘙痒病则毫无作用。

Experiments at the University of California showed that "scrapie" PrP resisted being broken down by protease enzymes, while normal healthy PrP did not.

加州大学实验室显示“羊瘙痒

Research the Effect of Anti-Allergic and Pruritus Cream on Treatment of Itching Skin Disease

抗敏止痒乳膏治疗瘙痒性皮肤病的疗效观察

Itching under the cast is a common problem.

病人常常感到管型下面的皮肤瘙痒。

Factors associated with pruritus in elderly diabetic patients

老年糖尿病伴瘙痒症的相关因素分析

Pruritus was moderate in 50.8% and severe in 23%.

发生瘙痒者中,50.8%呈中度瘙痒,23.0%呈重度瘙痒。

Treatment Chronic Itch of Skin on Enriching the Blood and Moistening Dryness in 48 Cases

养血润燥法治疗慢性瘙痒性皮肤病48例

Clinical Study of "Yao Xue Zhi Yang Pian" and "Xiao Yan Zhi Yang Shuang" in the Treatment of Senile Pruritus;

养血止痒片及消炎止痒霜治疗血虚风燥型老年性皮肤瘙痒病临床研究

Severe itching, often of undamaged skin.

瘙痒严重的瘙痒，经常指未受损伤的皮肤出现的瘙痒

This lotion relieves itching.

这药剂可减轻瘙痒。

Treatment and nursing care of pruritus in toxuria patients undergoing maintenance hemodialysis

维持性血液透析尿毒症病人瘙痒症的治疗与护理

The opium peptide should be relative with the onset of pruritus and Vidal disease.

结论．对片样肽确实与瘙痒症、神经性皮炎的发病有关。

ConclusionThe cream has good effects on neurodermatitics, chronic eczema, itch and psorcasis.

结论该制剂对神经性皮炎、性湿疹、屑病、肤瘙痒等有良好疗效。

Multiple Factors Analysis and Case-Control Study of Therapy of Uremic Pruritus;

尿毒症瘙痒多因素分析及治疗的临床病例对照研究

A CASE-CONTROL STUDY ON RISK FACTORS OF 410 MALE SENILE PRURITUS

410名男性老年瘙痒症患者危险因素病例对照研究

A chronic skin disease having various causes, marked by the eruption of pale, dome - shaped papules that itch severely.

痒疹一种由各种原因引起的慢性皮肤病，症状为出现小疹和引起严重瘙痒的穹状的丘疹

The scrapie agent in sheep may be similar to viroids.

绵羊的搔痒病因子可能也是类病毒。

Effect of SangLongZhiYang Pill on Treatment of Pruritus and Modulation of Levels of Itching Mediators;

桑龙止痒丸止痒作用及对瘙痒介质影响的研究